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Prereq: GIR:BIOL, GIR:CHEM
Units: 3-0-9

Analysis of potentially important risk factors for common diseases in the general environment and the workplace: air-, food- and water-borne chemicals; subclinical infections; diet and lifestyle choices. Analysis of history of changes in common disease rates. General paradigm of environmental sources and exposure of human subpopulations, uptake, internal distribution and metabolism of xenobiotics. Measurement of xenobiotic chemicals and allobiotic life forms in human tissues. Potential pathways of induced pathogenesis: mutagenesis, inflammation, hormonal mimicry.

W. Thilly, R. McCunney

Materials from this class are available on OpenCourseWare.